The condition of the officer was not immediately known.
The shooting happened in the area of Landale Street, just east of Laurel Canyon Boulevard, near Campbell Hall Episcopal school just before 8 pm, CHP said.
Video from AIR7HD showed multiple law enforcement units congregated in the area as they canvassed for clues.
AIR7HD followed an ambulance, believed to be carrying the officer, from the scene to Cedars-Sinai Medical Center. The ambulance was escorted by several police units.
A large police presence surrounded an apartment complex in the area of Saticoy Street and Haskell Avenue in Van Nuys, where the shooter is believed to be holed up.
A car matching the suspect vehicle description was found near the apartment complex.
It was not immediately known if anyone had been arrested.
The investigation is ongoing.
This is a developing story. Updated information will be added here as it becomes available.
Copyright © 2022 KABC Television, LLC. All rights reserved.